A short overview of vitamin C and selected cells of the immune system-Reference-Cited by-同舟云学术

A short overview of vitamin C and selected cells of the immune system

Published:2011-02-01 Issue:1 Volume:6 Page:1-10
ISSN:2391-5463
Container-title:Open Medicine
language:
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Author:

Pavlovic Voja¹,Sarac M.²

Affiliation:

1. 1Institute of Physiology, Medical Faculty, University in Nis, 18000, Nis, Serbia

2. 2Medical Faculty, University in Nis, 18000, Nis, Serbia

Abstract

AbstractVitamin C (ascorbic acid) is an essential water-soluble nutrient that primarily exerts its effect on a host defense mechanisms and immune homeostasis and is the most important physiological antioxidant. Stable intake of vitamin C is essential for life in humans because the body does not synthesize it. Even the numerous studies have demonstrated that vitamin C supplementation stimulates the immune system, prevents DNA damage and significantly decreases the risk of a wide range of pathologies; the potential protective mechanisms are still largely unknown. This review summarizes the recently known facts about the role of vitamin C on the selected cells of the immune system and potential molecular mechanisms involved. Further, in this review, many new data about the positive effects of vitamin C on the immune system, potential toxicological effects, vitamin C supplementation in disease development, as well as some proposed mechanisms of vitamin C activity, are discussed.

Publisher

Walter de Gruyter GmbH

Subject

General Medicine

Link

http://link.springer.com/content/pdf/10.2478/s11536-010-0066-x.pdf

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