1. 1Department of Anaesthesiology and Surgical Intensive Care Medicine, University Medical Centre Mannheim, 68167, Mannheim, Germany
2. 2Centre of Colo-proctology, 68165, Mannheim, Germany
3. 3Department of Medical Statistics, University Medical Centre Mannheim, 68167, Mannheim, Germany
4. 4Department of Anaesthesia, Intensive Care and Pain Therapy, University of Parma, 43100, Parma, Italy