New approaches in layer by layer synthesis of collagen/hydroxyapatite composite materials

Abstract

AbstractThe aim of this work was to increase our understanding of collagen (COLL)/ hydroxyapatite (HA) composite materials; more specifically, we focused on the study of the influence of the precursorconcentrations over the final content of deposited HA. We found that the increase of the precursor concentrations led to better mineralization (on the basis of the content of deposited mineral phase). Regardless of the precursor concentrations, the content of the deposited amount was found to increase with the increase of the number of deposited layers. Quantification of the mineral phase amount was achieved by gravimetric determination. Based on the determined deposition equation the number of layers can be easily determined in order to obtain composite materials with desired content of mineral phase.