Elastographic and morphological testicular changes in hypothyroidism – an experimental study-Reference-Cited by-同舟云学术

Elastographic and morphological testicular changes in hypothyroidism – an experimental study

Published:2018-09-01 Issue:3 Volume:62 Page:347-352
ISSN:2450-8608
Container-title:Journal of Veterinary Research
language:en
Short-container-title:

Author:

Gołyński Marcin¹,Dębiak Piotr²,Gołyńska Magdalena¹,Myśliwiec Ewa¹,Szkodziak Piotr³,Kalisz Grzegorz⁴,Śmiech Anna⁵,Lutnicki Krzysztof¹,Szczepanik Marcin¹

Affiliation:

1. Department and Clinic of Animal Internal Diseases , Lublin , Poland

2. Laboratory of Radiology and Ultrasonography , Department and Clinic of Animal Surgery , Faculty of Veterinary Medicine , University of Life Sciences , 20-612 Lublin , Poland

3. 3 Chair and Department of Gynaecology , Medical University , 20-954 Lublin , Poland

4. Department of Biopharmacy , Chair of Chemistry , Faculty of Pharmacy with Medical Analytics Division , Medical University of Lublin , 20-093 Lublin , Poland

5. Sub-Department of Pathomorphology and Forensic Medicine , Lublin , Poland

Abstract

Abstract Introduction Methimazole-induced hypothyroidism is a clinical problem in the treatment of hyperthyroidism in people and animals and is an example of metabolic disease that can lead to fertility disorders and can give elastographic testicular changes. Material and Methods Ultrasound elastography using the Esaote MyLab Twice ultrasound system and a morphological examination of testes were performed in seven methimazole-administered (group E) and seven healthy rats (group C). Results The elasticity ratio of strains in the scrotal wall of the near-field test area to testicular tissue (ELX-T-RAT) and hardness percentage of strained tissues in the defined area of a testicle (ELX-T%HRD) in group E were statistically significantly lower than in group C. The degree of spermatogenesis was statistically significantly higher in group E than in group C and similarly seminiferous tubule diameters in group E were statistically significantly higher than in group C. Body weight and testicular weight in group E were statistically significantly lower than in group C. Conclusion Changes in the elastographical parameters of testes may result from disorders secondary to hypothyroidism. The usefulness of elastography is noteworthy in the case of evaluation of testis function in patients with some metabolic disorders.

Publisher

Walter de Gruyter GmbH

Subject

General Veterinary

Link

https://www.sciendo.com/pdf/10.2478/jvetres-2018-0049

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