Focal liver lesions other than hepatocellular carcinoma in cirrhosis: Diagnostic challenges

Author:

Möller Kathleen1,Safai Zadeh Ehsan2,Görg Christian2,Dong Yi3,Cui Xinwu4,Lim Adrian5,Molo Chiara de6,Serra Carla6,Martín Algíbez Ana7,Berzigotti Analisa7,Piscaglia Fabio8,Faiss Siegbert1,Dietrich Christoph F.9

Affiliation:

1. SANA Hospital Lichtenberg, Medical Department I/Gastroenterology , Berlin 10365 , Germany

2. Interdisciplinary Center of Ultrasound Diagnostics, University Hospital Giessen and Marburg, Philipps University Marburg , Marburg 35033 , Germany

3. Department of Ultrasound, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine , Shanghai 200092 , China

4. Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan 430030 , Hubei Province , China

5. Imperial College London and Healthcare NHS Trust , London NW1 5QH , UK

6. Interventional, Diagnostic and Therapeutic Ultrasound Unit, Department of Medical and Surgical Sciences, IRCCS, Azienda Ospedaliero-Universitaria Sant' Orsola Malpighi Hospital , Bologna 40138 , Italy

7. University Clinic for Visceral Surgery and Medicine, INSELSPITAL, University Hospital of Bern , Bern 3010 , Switzerland

8. Division of Internal Medicine, Hepatobiliary and Immunoallergic Diseases, IRCCS Azienda Ospedaliero-Universitaria di Bologna , Bologna 40138 , Italy

9. Department of Internal Medicine (DAIM), Hirslanden Private Hospital Beau Site, Salem and Permanence , Bern CH-3013 , Switzerland

Abstract

Abstract Liver cirrhosis is associated with regenerative nodules and an increased risk of developing hepatocellular carcinoma (HCC). However, other benign and malignant liver lesions may also occur. Differentiating the other lesions from HCC is important for further therapeutic decisions. This review discusses the characteristics of non-HCC liver lesions in cirrhosis and their consequent appearance on contrast-enhanced ultrasonography (CEUS) with consideration of other imaging. Knowledge of this data would be helpful in avoiding misdiagnoses.

Publisher

Walter de Gruyter GmbH

Subject

Internal Medicine

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