Affiliation:
1. University Ss. Cyril and Methodius - Skopje , Faculty of Veterinary Medicine St. “Lazar Pop-Trajkov” 5-7 , Skopje , R. N. Macedonia
Abstract
Abstract
Lymphoma is the most common hematopoietic tumor in dogs. The standard diagnostic approach and staging includes detailed clinical history, physical examination and extended laboratory workup including lymph node cytology. Multidrug chemotherapy is the main treatment of the disease. Often, owners are concerned about the side effects of the treatment and the quality of life of their dog during chemotherapy. The aim of this study was to analyze the health related wellbeing of the patients with lymphoma previous, during and at the end of the chemotherapy. Five patients with multicentric lymphoma were monitored in three phases (beginning, middle and end of chemotherapy). The monitoring included clinical examination, laboratory analyses and a questionnaire for the owner. Results revealed significant improvement (p< 0.1) of the basic red blood cells parameters (RBC, PCV and Hb), platelets (PLT) as well as liver enzymes (ALT, AST) and protein status (total protein and globulin). Regarding the life quality assessed by the owners, dogs' appetite, general health compared to each visit and the current quality of life were significantly improved (p<0.1) and all of the owners were satisfied with the decision for chemotherapy.
Reference25 articles.
1. 1. Vail DM: Hematopoietic tumors. In: Textbook of Veterinary Internal Medicine, 5th edn. Eds Ettinger SJ and Feldman EC. Philadelphia: W. B. Saunders; 2000, 507–522.
2. 2. Merlo DF, Rossi L, Pellegrino C, Ceppi M, Cardellino U, Capurro C, Ratto A, Sambucco PL, Sestito V, Tanara G, Bocchini V: Cancer incidence in pet dogs: findings of the Animal Tumor Registry of Genoa, Italy. J Vet Intern Med 2008, 22(4):976–84.
3. 3. Zandvliet M: Canine lymphoma: a review. Vet Q 2016, 36(2):76–104.
4. 4. Gavazza A, Lubas G, Valori E, Gugliucci B: Retrospective survey of malignant lymphoma cases in the dog: clinical, therapeutical and prognostic features. Vet Res Commun 2008, 32(1):291–293.
5. 5. Sozmen M, Tasca S, Carli E, De Lorenzi D, Furlanello T, Caldin M: Use of fine needle aspirates and flow cytometry for the diagnosis, classification, and immunophenotyping of canine lymphomas. J Vet Diagn Invest 2005, 17:323–330.