Affiliation:
1. Institute for Information Transmission Problems of the Russian Academy of Sciences (Kharkevich Institute) , Moscow , Russia
Abstract
Abstract
Theoretical grounds of integral vectors of ventricular depolarization and repolarization and their sum, i.e., the spatial ventricular gradient, have been studied. A systematic description and biophysical interpretation of these parameters are presented based on the distribution of cardiomyocyte action potential parameters in the inhomogeneous bidomain model of the myocardium. Recent medical studies have shown high efficiency and predictive value of the ventricular gradient, its constituents and related parameters, such as the angle between the con-stituents, the acceleration of repolarization, etc. Simple examples for a myocardial strip clarify the relationship between the action potential parameters and the resulting ventricular gradient. An explanation with graphic illustration is given for the very informative decartogram of repolarization acceleration. The results obtained here are useful in the modeling of vectorcardiograms for various pathological conditions of the heart ventricles and for various characteristics of the cardiomyocyte action potential, which determine its shape.
Subject
Instrumentation,Biomedical Engineering,Control and Systems Engineering
Reference16 articles.
1. [1] Durrer, D. (1968). Electrical aspects of human cardiac activity: A clinical physiological approach to excitation and stimulation. Cardiovascular Research, 2 (1), 1-18.10.1093/cvr/2.1.1
2. [2] Wilson, F.N., MacLeod, A.G., Barker, P.S. (1933). Ditribution of the currents of action and injury displayed by heart muscle and other excitable tissues. In University of Michigan Studies, Scientific Series. University of Michigan Press, Vol. 10.
3. [3] Wilson, F.N., MacLeod, A.G., Barker, P.S., Johnson, F.D. (1934). The determination and the significance of the areas of the ventricular deflections of the electrocardiogram. American Heart Journal, 10, 46-61.10.1016/S0002-8703(34)90303-3
4. [4] Burch, G.E., Abildskov, A.A., Cronvich, J.A. (1954). A study of the spatial vectorcardiogram of the ventricular gradient. Circulation, 9, 267-275.10.1161/01.CIR.9.2.267
5. [5] Burger, H.C. (1957). A theoretical elucidation of the notion “ventricular gradient”. American Heart Journal, 53 (2), 240-246.10.1016/0002-8703(57)90211-9
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