Primary Burkitt Lymphoma of the Rectum
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Published:2023-08-01
Issue:3-4
Volume:77
Page:211-216
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ISSN:2255-890X
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Container-title:Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences.
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language:en
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Short-container-title:
Author:
Kokaine Linda12, Briede Inese34, Brikuns Andrejs12, Gardovskis Andris12, Gardovskis Jānis12
Affiliation:
1. 1 Department of Surgery , Rīga Stradiņš University , 16 Dzirciema Str., Rīga, LV-1007 , Latvia 2. 2 Pauls Stradiņš Clinical University Hospital , 13 Pilsoņu Str ., Rīga , , Latvia 3. 3 Department of Pathology , Rīga Stradiņš University , Rīga , LV-1007 , Latvia 4. 4 Institute of Pathology , Pauls Stradiņš Clinical University Hospital , 13 Pilsoņu Str ., Rīga , , Latvia
Abstract
Abstract
Burkitt lymphoma (BL) is a highly aggressive mature B-cell neoplasm with the highest incidence in a pediatric population. Three clinical subtypes of BL are known: sporadic, endemic, and immune deficiency associated. The most common site of involvement in the case of the sporadic form is an ileocecal region. We describe a rare case of sporadic BL in a 71-year-old male with a primary localisation in the rectum presenting with progressive bowel obstruction and rectal bleeding. The clinical evaluation involved colonoscopy, biopsy with a following morphological examination, computerised tomography of thorax, abdomen and pelvis, magnetic resonance imaging of pelvis, and laboratory analysis. Due to the unclear tumorous mass and progressive clinical symptoms, surgical treatment was applied – laparotomy, total mesorectal excision with the formation of permanent colostomy. Morphological examination of the specimen revealed a phenotype characteristic to BL. One month after the surgery, two single liver metastasis were detected. The patient received six courses of DA-EPOCH chemotherapy. Post-treatment radiological examinations revealed full clinical remission and disease-free survival for 68 months (5 years and 8 months).
Publisher
Walter de Gruyter GmbH
Subject
Multidisciplinary
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