Clinical Case of a Patient with Extranodal Diffuse Large B-Cell Lymphoma and Surgical Complications-Reference-Cited by-同舟云学术

Clinical Case of a Patient with Extranodal Diffuse Large B-Cell Lymphoma and Surgical Complications

Published:2023-06-01 Issue:1 Volume:16 Page:62-65
ISSN:1313-9053
Container-title:Journal of Biomedical and Clinical Research
language:en
Short-container-title:

Author:

Ilieva Ralitsa G.¹,Todorieva-Todorova Doroteya K.¹²,Hristov Ivaylo G.¹,Tsintsarska Vasilena P.¹

Affiliation:

1. 1 Clinic of Hematology , Dr Georgi Stranski University Hospital , Pleven , Bulgaria

2. 2 Department of Nephrology, Haematology and Gastroenterology , Medical University - Pleven , Bulgaria

Abstract

Summary Diffuse large B-cell lymphoma (DLBCL) is one of the most common types of non-Hodgkin lymphoma in adults. In most of the cases a complete remission is possible to obtain by applying conventional immunochemotherapy (rituximab in combination with cyclophosphamide, doxorubicin, vincristine, methylprednisolone or R-CHOP). Its effect depends on some risk factors, cellular origin of the lymphoma and to some extend – the localization when extranodal involvement is confirmed. We present the case of a patient with DLBCL of small intestine and non-specific clinical manifestation. Following treatment with standard therapy R-CHOP patient fail to achieve disease response and gastrointestinal track (GIT) complications were registered.

Publisher

Walter de Gruyter GmbH

Subject

General Medicine

Link

https://www.sciendo.com/pdf/10.2478/jbcr-2023-0009

Reference14 articles.

1. Swerdlow SH, Campo E, Pileri SA, Harris NL, Stein H, Siebert R, et.al. The 2016 revision of the World Health Organization classification of lymphoid neoplasms. Blood. 2016;127(20):2375-90.

2. Smith SD, Chen A, Spurgeon S, Okada C, Fan G, Dunlap J, et.al. Diffuse large B-cell lymphoma in adults aged 75 years and older: a single institution analysis of cause-specific survival and prognostic factors. Ther Adv Hematol. 2013;4(6):349-53.

3. Genova M, Grudeva J, Gercheva L, Kaleva V, Balatsenko G, Goranov S, et.al. [Diffuse large B-cell lymphoma]. In Genova M.,editor. [Bulgarian hematology guideline]. Varna. 2018. p. 304-12. Bulgarian

4. Li B, Shi YK, He XH, Zou SM, Zhou SY, Dong M, et.al. Primary non-Hodgkin lymphomas in the small and large intestine: clinicopathological characteristics and management of 40 patients. Int J Hematol. 2008;87(4):375-81.

5. Gascoyne DR. The biology of diffuse large B-cell lymphoma (DLBCL). Pathology. 2014;46 (Suppl 1):S 32.