Evaluation of binding properties of Plantago psyllium seed mucilage

Abstract

Evaluation of binding properties ofPlantago psylliumseed mucilageMucilage extracted fromPlantago psylliumseeds was evaluated for inertness and safety parameters. The suitability of psyllium mucilage for a pharmaceutical binder was assessed in paracetamol tablets. Properties of the granules prepared using different concentrations of psyllium mucilage was compared with PVP and tragacanth. Psyllium mucilage at 5 % (m/m) was found to be comparable with 3 % (m/m) of PVP. Investigated paracetamol tablets indicated that psyllium mucilage can retard the drug release.