Dietary Effect of S-Methylmethionine Sulfonium Chloride on Growth, Serum Biochemical Parameters, Body Composition, and Expression of Some Related Genes in Oreochromis niloticus

Author:

Gewida Ahmed G.A.1,Abouzed Tarek Kamal2,Abdelghany Mohamed F.1,Khames Doaa K.3,Zayed Mohamed M.4,Elsawy Hanan B.5,AbdEl-Kader Marwa F.6,Naiel Mohammed A.E.7

Affiliation:

1. 1 Department of Fish Production, Faculty of Agriculture , Al-Azhar University , Cairo , Egypt

2. 2 Department of Biochemistry, Faculty of Veterinary Medicine , Kafrelsheikh University , Kafrelsheikh , Egypt

3. 3 Fish Nutrition Department , Central Lab for Aquaculture Research (CLAR), Abassa, Agriculture Research Center , Giza , Egypt

4. 4 Department of Aquaculture, Faculty of Aquatic and Fisheries Sciences , Kafrelsheikh University , Kafrelsheikh , Egypt

5. 5 Department of Nutrition and Clinical Nutrition, Faculty of Veterinary Medicine , Kafrelsheikh University , Kafrelsheikh , Egypt

6. 6 Department of Fish Health and Management, Sakha Aquaculture Research Unit , Central Laboratory for Aquaculture Research, A.R.C, Kafrelsheikh , Egypt

7. 7 Department of Animal Production, Faculty of Agriculture , Zagazig University , Zagazig , Egypt

Abstract

Abstract The main objective of the current trial was to investigate the impacts of tilapia diets supplemented with S-methylmethionine sulfonium chloride (MMSC) on the growth performance, feed efficiency, body analysis, blood biochemistry and regulation of myostatin (MSTN) and insulin-like growth factor-1 (IGF-1) genes of nile tilapia (Oreochromis niloticus). The experimental fish (n=180) weighing 22.4±0.17 g were allocated randomly into three equal groups in triplicate as follows; the control group received an un-supplemented diet; the other two groups received two different levels of MMSC (0.2 and 0.4 g/kg) for eight weeks. The obtained findings demonstrated that tilapia diets enriched with small dosages of MMSC considerably (P<0.05) enhanced all assessed growth performance and feed efficiency indicators when compared with the control group. When compared to the control group, tilapia meals supplemented with 0.2 g MMSC significantly (P<0.05 or 0.01) raised blood protein profile, particularly total protein and globulin levels. Contrarily, blood creatinine levels were significantly (P<0.01) reduced in the group of tilapia fed diets containing MMSC (0.2 or 0.4 g/kg) compared to the group without receiving any supplementation. Whereas, fish body analysis showed higher significant increases in crude protein and ether extract levels (P<0.01) as well as reduced ash content (P<0.05) in the fish group that received lower MMSC doses in comparison to other treated and control groups. In addition, MMSC dietary supplementation significantly downregulated the expression of MSTN and upregulated IGF-1 mRNA expression compared with the control group. Additionally, both dosages of MMSC supplementation modestly enhanced the intestinal villus histomorphometric score indices with observed tall, thick, and various broad tips in comparison to the control group. In conclusion, it could be recommended that fish diets supplemented with 0.2 g MMSC per kg diet may promote the growth and general health status of Nile Tilapia.

Publisher

Walter de Gruyter GmbH

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3