Comparison of <i>BoLA-DRB3</i> genetic diversity among polish red and white (PRW) and polish holstein-friesian (PHF) cattle-Reference-Cited by-同舟云学术

Comparison of BoLA-DRB3 genetic diversity among polish red and white (PRW) and polish holstein-friesian (PHF) cattle

Published:2023-10-05 Issue:0 Volume:0 Page:
ISSN:2300-8733
Container-title:Annals of Animal Science
language:en
Short-container-title:

Author:

Zielak-Steciwko Anna E.¹,Strzała Tomasz²,Luboń Bartosz²,Smołucha Grzegorz³,Zachwieja Andrzej¹,Płoneczko-Janeczka Katarzyna⁴,Rypuła Krzysztof⁴

Affiliation:

1. 1 Institute of Animal Breeding , Wrocław University of Environmental and Life Sciences , Chełmońskiego 38c, 50-375 Wrocław , Poland

2. 2 Department of Genetics , Wrocław University of Environmental and Life Sciences , Kożuchowska 7, 51-631 Wrocław , Poland

3. 3 Department of Animal Molecular Biology , National Research Institute of Animal Production , 32-083 Balice n. Kraków , Poland

4. 4 Department of Epizootiology and Clinic of Bird and Exotic Animals , Wrocław University of Environmental and Life Sciences , Norwida 31, 50-375 Wrocław , Poland

Abstract

Abstract Cattle breeding in Poland, including the maintenance of indigenous breeds, is exposed to the occurrence of many diseases of infectious and non-infectious etiologies. Bovine MHC (BoLA)-DRB3 is a highly polymorphic gene that plays an important role in the immune response to antigens. This pilot study aimed to analyze BoLA-DRB3 genetic diversity among Polish Red and White (PRW) and Polish Holstein-Frisian (PHF) cattle. DNA sequencing revealed haplotypes for 48 out of 106 PRW and 10 out of 26 PHF cows. Analysis indicated 42 alleles detected in the PRW breed and 16 in the PHF animals. Interestingly, within the PRW breed three alleles BOLA03100|BoLA-DRB3*001:01|554, BOLA03113|BoLA-DRB3*009:02|270 and BOLA03302|BoLA-DRB3*049:01|236 were observed in 24 cows. Overall, the presented study demonstrated the genetic diversity of the BoLA-DRB3 gene in the indigenous cattle breed Polish Red and White cattle breed for the first time. The acquired results broaden the knowledge of BoLA-DRB3 diversity in cattle, whose genetic variants promote resistance or susceptibility to viral or bacterial diseases.

Publisher

Walter de Gruyter GmbH

Link

https://www.sciendo.com/pdf/10.2478/aoas-2023-0091

Reference22 articles.

1. Bett R.C., Okeyo M.A., Malmfors B., Johansson K., Agaba M., Kugonza D.R., Bhuiyan A.K.F.H., Filho A.E.V., Mariante A.S., Mujibi F.D., Philipsson J. (2013). Cattle Breeds: Extinction or Quasi-Extant? Resources, 2: 335–357.

2. Behl J.D., Verma N.K., Tyagi N., Mishra P., Behl R., Joshi B.K. (2012). The major histocompatibility complex in bovines: a review. ISRN Vet Sci., 872710.

3. Bohórquez M.D., Ordoñez D., Suárez C.F., Vicente B., V.ieira C., López-Abán J., Muro A., Ordóñez I., Patarroyo M.A. (2020). Major Histocompatibility Complex Class II (DRB3) Genetic Diversity in Spanish Morucha and Colombian Normande Cattle Compared to Taurine and Zebu Populations. Front. Genet., 10: 1293.

4. Ellis S.A., Bontrop R.E., Antczak D.F., Ballingall K., Davies C.J., Kaufman J., Kennedy L.J., Robinson J., Smith D.M., Stear M.J., Stet R.J., Waller M.J., Walter L., Marsh S.G. (2006). ISAG/IUIS-VIC Comparative MHC Nomenclature Committee report, 2005. Immunogenetics 57: 953–958.

5. Glass E.J. (2004). Genetic variation and responses to vaccines. Anim. Health. Res. Rev., 5: 197–208.