Development of Graphene-Based Materials with the Targeted Action for Cancer Theranostics
-
Published:2024-08
Issue:8
Volume:89
Page:1362-1391
-
ISSN:0006-2979
-
Container-title:Biochemistry (Moscow)
-
language:en
-
Short-container-title:Biochemistry Moscow
Author:
Semenov Konstantin N.,Shemchuk Olga S.,Ageev Sergei V.,Andoskin Pavel A.,Iurev Gleb O.,Murin Igor V.,Kozhukhov Pavel K.,Maystrenko Dmitriy N.,Molchanov Oleg E.,Kholmurodova Dilafruz K.,Rizaev Jasur A.,Sharoyko Vladimir V.
Abstract
Abstract
The review summarises the prospects in the application of graphene and graphene-based nanomaterials (GBNs) in nanomedicine, including drug delivery, photothermal and photodynamic therapy, and theranostics in cancer treatment. The application of GBNs in various areas of science and medicine is due to the unique properties of graphene allowing the development of novel ground-breaking biomedical applications. The review describes current approaches to the production of new targeting graphene-based biomedical agents for the chemotherapy, photothermal therapy, and photodynamic therapy of tumors. Analysis of publications and FDA databases showed that despite numerous clinical studies of graphene-based materials conducted worldwide, there is a lack of information on the clinical trials on the use of graphene-based conjugates for the targeted drug delivery and diagnostics. The review will be helpful for researchers working in development of carbon nanostructures, material science, medicinal chemistry, and nanobiomedicine.
Publisher
Pleiades Publishing Ltd
Reference198 articles.
1. Shin, S. R., Li, Y. C., Jang, H. L., Khoshakhlagh, P., Akbari, M., Nasajpour, A., Zhang, Y. S., Tamayol, A., and Khademhosseini, A. (2016) Graphene-based materials for tissue engineering, Adv. Drug Deliv. Rev., 105, 255-274,
https://doi.org/10.1016/j.addr.2016.03.007. 2. Lin, J., Huang, Y., and Huang, P. (2018) Graphene-Based Nanomaterials in Bioimaging, in Biomedical Applications of Functionalized Nanomaterials: Concepts, Development and Clinical Translation, Elsevier, pp. 247-287,
https://doi.org/10.1016/b978-0-323-50878-0.00009-4. 3. Feng, L. L., Wu, Y. X., Zhang, D. L., Hu, X. X., Zhang, J., Wang, P., Song, Z. L., Zhang, X. B., and Tan, W. (2017) Near infrared graphene quantum dots-based two-photon nanoprobe for direct bioimaging of endogenous ascorbic acid in living cells, Anal. Chem., 89, 4077-4084,
https://doi.org/10.1021/acs.analchem.6b04943. 4. Thapa, R. K., Kim, J. H., Jeong, J. H., Shin, B. S., Choi, H. G., Yong, C. S., and Kim, J. O. (2017) Silver nanoparticle-embedded graphene oxide-methotrexate for targeted cancer treatment, Colloids Surf. B Biointerfaces, 153, 95-103,
https://doi.org/10.1016/j.colsurfb.2017.02.012. 5. Zhang, C., Liu, Z., Zheng, Y., Geng, Y., Han, C., Shi, Y., Sun, H., Zhang, C., Chen, Y., Zhang, L., Guo, Q., Yang, L., Zhou, X., and Kong, L. (2018) Glycyrrhetinic acid functionalized graphene oxide for mitochondria targeting and cancer treatment in vivo, Small, 14, 1703306,
https://doi.org/10.1002/smll.201703306.
|
|