Knockout of BAX and BAK1 Genes and Overexpression of BCL2, BECN1 Genes Increase Lifespan and the Maximum Density of a CHO-S Cell Culture
Author:
Publisher
Pleiades Publishing Ltd
Subject
Applied Microbiology and Biotechnology,Biochemistry
Link
https://link.springer.com/content/pdf/10.1134/S0003683823080057.pdf
Reference26 articles.
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4. Fussenegger M., Fassnacht D., Schwartz R., Zanghi J.A., Graf M., Bailey J.E., Portner R. Regulated overexpression of the survival factor bcl-2 in CHO cells increases viable cell density in batch culture and decreases DNA release in extended fixed-bed cultivation, Cytotechnology, 2000, vol. 32, no. 1, pp. 45–61. https://doi.org/10.1023/A:1008168522385
5. Kim, Y.G., Kim, J.Y., Mohan, C., and Lee, G.M., Effect of Bcl-Xl overexpression on apoptosis and autophagy in recombinant Chinese hamster ovary cells under nutrient-deprived condition, Biotechnol. Bioeng., 2009, vol. 103, no. 4, pp. 757–766. https://doi.org/10.1002/bit.22298
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