Abnormal mTOR Signaling Pathway Activity in Autism Spectrum Disorders: Prospects of Mechanism-Based Therapy
Author:
Publisher
Pleiades Publishing Ltd
Subject
Structural Biology,Biophysics
Link
https://link.springer.com/content/pdf/10.1134/S0026893323020206.pdf
Reference57 articles.
1. Yoo H. 2015. Genetics of autism spectrum disorder: current status and possible clinical applications. Exp. Neurobiol. 24, 257–272. https://doi.org/10.5607/en.2015.24.4.257
2. Winden K.D., Ebrahimi-Fakhari D., Sahin M. 2018. Abnormal mTOR activation in autism. Annu. Rev. Neurosci. 41, 1–23. https://doi.org/10.1146/annurev-neuro-080317-061747
3. Bockaert J., Marin P. 2015. mTOR in brain physiology and pathologies. Physiol. Rev. 95, 1157–1187. https://doi.org/10.1152/physrev.00038.2014
4. Trifonova E.A, Klimenko A.I., Mustafin Z.S., Lashin S.A., Kochetov A.V. 2019. The mTOR signaling pathway activity and vitamin D availability control the expression of most autism predisposition genes. Int. J. Mol. Sci. 20, E6332. https://doi.org/10.3390/ijms20246332
5. Zoghbi H.Y., Bear M.F. 2012. Synaptic dysfunction in neurodevelopmental disorders associated with autism and intellectual disabilities. Cold Spring Harb. Perspect. Biol. 4, a009886. https://doi.org/10.1101/cshperspect.a009886
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