Affiliation:
1. I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia
2. I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia; Lomonosov Moscow State University
3. N.N. Burdenko Main Military Clinical Hospital, Ministry of Defence of Russia
4. Moscow Institute of Physics and Technology (National Research University)
Abstract
Introduction. Timely maxillofacial orthopedic care is aimed at leveling the message of the oral cavity with the nasal cavity and its paranasal sinuses, orbit, helps to improve swallowing, speech, breathing and salivation. The objective of this work is to demonstrate the possibility of application of a polymethyl methacrylate prosthesis with a superhydrophobic modified surface directly on the operating table, as well as to demonstrate the possibility of using in the shortest postoperative period. Materials and methods. Patient Z., 28 years old, clinical diagnosis: chondrosarcoma of the upper jaw on the right, Т2N0M0, stage 2. A resection of the upper jaw was proposed with simultaneous reconstructive treatment and the application of a dental resection forming denture of the upper jaw. To form a hydrophobic surface, the prosthesis was modified with a high-frequency plasma of sulfur hexafluorides. The study of the quantitative and qualitative composition of microflora on the surface of the resection forming prosthesis was carried out after transportation of the prosthesis from the dental laboratory, after processing of high-frequency plasma of sulfur hexafluoride and before applying the resection forming prosthesis, 3, 7 days after the prosthesis was applied. Results. After modification of sulfur hexafluoride in the medium, the contact angle of contact with distilled water increased, the critical surface tension decreased compared to the initial one, and the hydrophobic properties were increased. Conditionally pathogenic microflora in a diagnostically significant amount was cultivated from the surface of the resection forming prosthesis obtained from the dental laboratory. Bacterial seeding after modification in the plasma of sulfur hexafluoride showed the absence of microflora strains; a slight increase in opportunistic microflora was obtained on days 3 and 7 after application of the prosthesis. In the immediate postoperative period (3 days), the patient complained of pain and discomfort associated with the surgical stage. Conclusions. The presented clinical case indicate that the superhydrophobic surface modified by sulfur hexafluoride contributes to a more stable healing of the postoperative defect.
Publisher
Publishing House ABV Press
Subject
Pharmacology (medical),Cancer Research,Radiology, Nuclear Medicine and imaging,Oncology,Otorhinolaryngology,Surgery