Affiliation:
1. N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
2. A.S. Loginov Moscow Clinical Scientific Center of the Moscow Healthcare Department
Abstract
This review aims to provide up-to-date information on the factors associated with an increased risk of vaginal fistula in women with cervical cancer, as well as on methods of their prevention and treatment. It includes data on various types of vaginal fistulas in cervical cancer patients and risk factors for their development, according to foreign and Russian research articles published over the last 20 years. Cervical cancer is one of the most challenging oncological diseases in the Russian Federation, because it is detected at stage III–IV in more than 30 % of women. Such a high incidence of cervical cancer and the need for radiotherapy determine high risk of fistulas, which significantly impairs the quality of life. Thus, identification of factors associated with vaginal fistulas, as well as methods of their prevention and treatment remains a highly relevant task for the Russian healthcare system.
Publisher
Publishing House ABV Press
Reference51 articles.
1. WHO Handbook for health inequality monitoring. Available at: https://www.who.int/gho/health_equity/handbook/en/.
2. Malignant tumors in Russia in 2019. (incidence and mortality). Ed. by A.D. Kaprin, V.V. Starinskiy, A.O. Shakhzodova. Moscow: P.A. Herzen Moscow Oncology Research Institute – a branch of the National Medical Research Center of Radiology, Ministry of Health of Russia, 2020. 252 p. (In Russ.).
3. Situation with cancer care in Russia in 2019. Ed. by A.D. Kaprin, V.V. Starinskiy, A.O. Shakhzadova. Moscow: P.A. Herzen Moscow Oncology Research Institute – a branch of the National Medical Research Center of Radiology, Ministry of Health of Russia, 2020. 239 p. (In Russ.).
4. Lind H., Waldenstrom A.C., Dunberger G. et al. Late symptoms in long-term gynaecological cancer survivors after radiation therapy: a population-based cohort study. Br J Cancer 2011;105:737Y745. DOI: 10.1038/bjc.2011.315.
5. Kirwan J.M., Symonds P., Green J.A. et al. A systematic review of acute and late toxicity of concomitant chemoradiation for cervical cancer. Radiother Oncol 2003;68:217Y226. DOI: 10.1016/s0167-8140(03)00197-x.