Malformations of the cerebral cortex and epilepsy. Clinical lecture

Author:

Kotov A. S.1ORCID,Firsov K. V.1ORCID

Affiliation:

1. M.F. Vladimirsky Moscow Regional Research Clinical Institute

Abstract

Malformations of the cerebral cortex are often the causes of epilepsy. The latest changes in their classification are summarized. The description of lissencephaly and Miller–Dicker syndrome, pachygyria, polymicrogyria, hemimegaloencephaly, holoprosencephaly, schizencephaly, gray matter heterotopia is given. The features of epilepsy in these diseases are described. Magnetic resonance imaging scans for focal cortical dysplasia, polymicrogyria, and gray matter heterotopia are presented.

Publisher

Publishing House ABV Press

Subject

Neurology (clinical),Pediatrics, Perinatology and Child Health

Reference37 articles.

1. Mukhin K.Yu., Bezrukova I.S., Tyagun N.S. et al. Miller–Dicker syndrome. Russkiy zhurnal detskoy nevrologii = Russian Journal of Child Neurology 2008;3(3):61–6. (In Russ.)

2. Serezhkina A.V., Minenkova T.A., Razinkova N.S. et al. Clinical case of semilobar holoprosencephaly in a child. Mezhdunarodnyy studencheskiy nauchnyy vestnik = International Student Scientific Bulletin 2020;(2):49. (In Russ.)

3. Barkovich A.J., Guerrini R., Kuzniecky R.I. et al. A developmental and genetic classification for malformations of cortical development: update 2012. Brain 2012;135(Pt 5):1348–69. DOI: 10.1093/brain/aws019

4. Barkovich A.J., Kuzniecky R.I. Gray matter heterotopia. Neurology 2000;55(11):1603–8. DOI: 10.1212/wnl.55.11.1603

5. Barkovich A.J. MRI analysis of sulcation morphology in polymicrogyria. Epilepsia 2010;51(Suppl 1):17–22. DOI: 10.1111/j.1528-1167.2009.02436.x

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