Two-year Outcomes of Infliximab Discontinuation in Patients with Rheumatoid Arthritis: A Retrospective Analysis from a Single Center

Author:

Takai Chinatsu1,Ito Satoshi1,Kobayashi Daisuke12,Nemoto Tetsuya13,Lee Hyunho14,Abe Asami1,Otani Hiroshi1,Nakazono Kiyoshi1,Murasawa Akira1,Ishikawa Hajime1

Affiliation:

1. Department of Rheumatology, Niigata Rheumatic Center, Japan

2. Division of Clinical Nephrology and Rheumatology Niigata University Graduate School of Medical and Dental Sciences, Japan

3. Department of Orthopaedic Surgery, Showa University School of Medicine, Japan

4. Department of Orthopaedic Surgery, Nihon University School of Medicine, Japan

Publisher

Japanese Society of Internal Medicine

Subject

General Medicine,Internal Medicine

Reference19 articles.

1. 1. Maini R, St Clair EW, Breedveld F, et al. Infliximab (chimeric anti-tumour necrosis factor alpha monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial. ATTRACT Study Group. Lancet 4: 1932-1939, 1999.

2. 2. van der Bijl AE, Goekoop-Ruiterman YP, de Vries-Bouwstra JK, et al. Infliximab and methotrexate as induction therapy in patients with early rheumatoid arthritis. Arthritis Rheum 56: 2129-2134, 2007.

3. 3. Tanaka Y, Takeuchi T, Mimori T, et al.; RRR study investigators. Discontinuation of infliximab after attaining low disease activity in patients with rheumatoid arthritis: RRR (remission induction by Remicade in RA) study. Ann Rheum Dis 69: 1286-1291, 2010.

4. 4. Prevoo ML, van't Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL. Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum 38: 44-48, 1995.

5. 5. Steinbrocker O, Traeger CH, Batterman RC. Therapeutic criteria in rheumatoid arthritis. J Am Med Assoc 25: 659-662, 1949.

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