Epigenetic Inactivation of Tumor Suppressor SFRP2 and Point Mutation in KRAS Proto-Oncogene in Fistula - Associated Mucinous Type Anal Adenocarcinoma: Report of Two Cases
Author:
Affiliation:
1. Department of General Surgery, Faculty of Medicine, Cumhuriyet University
2. Department of Medical Genetics, Faculty of Medicine, Cumhuriyet University
3. Department of Pathology, Faculty of Medicine, Cumhuriyet University
Publisher
Japanese Society of Internal Medicine
Subject
General Medicine,Internal Medicine
Link
http://www.jstage.jst.go.jp/article/internalmedicine/49/15/49_15_1637/_pdf
Reference25 articles.
1. Malignant tumors of the anus
2. SFRP2 methylation in fecal DNA—a marker for colorectal polyps
3. Hypermethylated SFRP2 gene in fecal DNA is a high potential biomarker for colorectal cancer noninvasive screening
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3. Secreted Frizzled-Related Protein 2 (sFRP2) promotes osteosarcoma invasion and metastatic potential;BMC Cancer;2016-11-08
4. Identification of diagnostic markers in colorectal cancer via integrative epigenomics and genomics data;Oncology Reports;2015-05-19
5. Perianal Adenocarcinoma Associated with Anal Fistula: A Report of 11 Cases in a Single Institution Focusing on Treatment and Literature Review;HEPATO-GASTROENTEROL;2013
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