Diagnostic Values of Venous Peak Lactate, Lactate-to-pyruvate Ratio, and fold Increase in Lactate from Baseline in Aerobic Exercise Tests in Patients with Mitochondrial Diseases
Author:
Affiliation:
1. Department of Neurology, Graduate School of Medicine, The University of Tokyo, Japan
2. Department of Metabolism, Chiba Children's Hospital, Japan
3. Department of Molecular Neurology, Graduate School of Medicine, The University of Tokyo, Japan
Publisher
Japanese Society of Internal Medicine
Subject
General Medicine,Internal Medicine
Link
https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_8629-21/_pdf
Reference38 articles.
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2. 2. Liang C, Ahmad K, Sue CM. The broadening spectrum of mitochondrial disease: shifts in the diagnostic paradigm. Biochim. Biophys. Acta 1840 (4): 1360-1367, 2014.
3. 3. Suomalainen A, Elo JM, Pietiläinen KH, et al. FGF-21 as a biomarker for muscle-manifesting mitochondrial respiratory chain deficiencies: a diagnostic study. Lancet. Neurol 10 (9): 806-818, 2011.
4. 4. Davis RL, Liang C, Edema-Hildebrand F, Riley C, Needham M, Sue CM. Fibroblast growth factor 21 is a sensitive biomarker of mitochondrial disease. Neurology 81 (21): 1819-1826, 2013.
5. 5. Yatsuga S, Fujita Y, Ishii A, et al. Growth differentiation factor 15 as a useful biomarker for mitochondrial disorders. Ann. Neurol 78 (5): 814-823, 2015.
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