5. Leflunomide and Mizoribine.
Author:
Affiliation:
1. Department of Rheumatology, Tokyo Medical University Hospital
Publisher
Japanese Society of Internal Medicine
Subject
General Medicine
Link
https://www.jstage.jst.go.jp/article/naika/100/10/100_2929/_pdf
Reference14 articles.
1. 1) Herrmann ML, et al: Leflunomide: an immunomodulatory drug for the treatment of rheumatoid arthritis and other autoimmune diseases. Immunopharmacology 47 (2-3): 273-289, 2000.
2. 2) Urushibara M, et al: The antirheumatic drug leflunomide inhibits osteoclastogenesis by interfering with receptor activator of NF-kappa B ligand-stimulated induction of nuclear factor of activated T cells c1. Arthritis Rheum 50 (3): 794-804, 2004.
3. 3) Osiri M, et al: Leflunomide for the treatment of rheumatoid arthritis: a systematic review and metaanalysis. J Rheumatol 30 (6): 1182-1190, 2003.
4. 4) Kremer J, et al: Combination leflunomide and methotrexate (MTX) therapy for patients with active rheumatoid arthritis failing MTX monotherapy: open-label extension of a randomized, double-blind, placebo controlled trial. J Rheumatol 31 (8): 1521-1531, 2004.
5. 5) Grabar PB, et al: Dihydroorotate dehydrogenase polymorphism influences the toxicity of leflunomide treatment in patients with rheumatoid arthritis. Ann Rheum Dis 68 (8): 1367-1368, 2009.
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