Identification of pyrogallol from Awa-tea as an anti-allergic compound that suppresses nasal symptoms and IL-9 gene expression

Author:

Nakano Tomohiro1,Ikeda Mitsuhiro1,Wakugawa Tomoharu1,Kashiwada Yoshiki2,Kaminuma Osamu3,Kitamura Noriko4,Yabumoto Masam5,Fujino Hiromichi1,Kitamura Yoshiaki6,Fukui Hiroyuki57,Takeda Noriaki6,Mizuguchi Hiroyuki7

Affiliation:

1. Department of Molecular Pharmacology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima 770-8505, Japan

2. Department of Pharmacognosy, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima 770-8505, Japan

3. Department of Disease Model Research Institute of Radiation Biology and Medicine, Hiroshima University, Hiroshima 734-8553, Japan

4. Allergy and Immunology Project, The Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan

5. Medical Corporation Kinshukai, Osaka 558-0011, Japan

6. Department of Otolalyngology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima 770-8503, Japan

7. Laboratory of Pharmacology, Faculty of Pharmacy, Osaka Ohtani University, Osaka 584-8540, Japan

Publisher

University of Tokushima Faculty of Medicine

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference32 articles.

1. 1. Okubo K, Kurono Y, Ichimura K, Enomoto T, Okamoto Y, Kawauchi H, Suzaki H, Fujieda S, Masuyama K, Japanese Society of Allergology : Japanese guidelines for allergic rhinitis. Allrgol Int 66 : 205-219, 2017

2. 2. Mizuguchi H, Hatano M, Matsushita C, Umehara H, Kuroda W, Kitamura Y, Takeda N, Fukui H : Repeated pretreatment with antihistamines suppresses transcriptional upregulations of histamine H1 receptor and interleukin-4 genes in toluene-2,4-diisocyanate-sensitized rats. J Pharmacol Sci 108 : 480-486, 2008

3. 3. Mizuguchi H, Kitamura Y, Kondo Y, Kuroda W, Yoshida H, Miyamoto Y, Hattori M, Fukui H, Takeda N : Preseasonal prophylactic treatment with antihistamines suppresses nasal symptoms and expression of histamine H1 receptor mRNA in the nasal mucosa of patients with pollinosis. Methods Find Exp Clin Pharmacol 32 : 745-748, 2010

4. 4. Kitamura Y, Nakagawa H, Fujii T, Sakoda T, Enomoto T, Mizuguchi H, Fukui H, Takeda N : Effects of antihistamine on up-regulation of histamine H1 receptor mRNA in the nasal mucosa of patients with pollinosis induced by controlled cedar pollen challenge in an environmental exposure unit. J Pharmacol Sci 129 : 183-187, 2015

5. 5. Das AK, Yoshimura S, Mishima R, Fujimoto K, Mizuguchi H, Dev S, Wakayama Y, Kitamura Y, Horio S, Takeda N, Fukui H : Stimulation of histamine H1 receptor up-regulates histamine H1 receptor itself through activation of receptor gene transcription. J Pharmacol Sci 103 : 374-382, 2007

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3