A hybrid CFD-PBPK model for naphthalene in rat and human with IVIVE for nasal tissue metabolism and cross-species dosimetry
Author:
Publisher
Informa UK Limited
Subject
Health, Toxicology and Mutagenesis,Toxicology
Link
http://www.tandfonline.com/doi/pdf/10.3109/08958378.2014.896059
Reference48 articles.
1. Naphthalene: A Respiratory Tract Toxicant and Carcinogen for Mice
2. TOXICITY AND CARCINOGENICITY STUDY IN F344 RATS FOLLOWING 2 YEARS OF WHOLE-BODY EXPOSURE TO NAPHTHALENE VAPORS
3. DOSIMETRIC ADJUSTMENT FACTORS FOR METHYL METHACRYLATE DERIVED FROM A STEADY-STATE ANALYSIS OF A PHYSIOLOGICALLY BASED CLEARANCE-EXTRACTION MODEL
4. Comparison of Pulmonary/Nasal CYP2F Expression Levels in Rodents and Rhesus Macaque
5. Bioactivation of the Pulmonary Toxicants Naphthalene and 1-Nitronaphthalene by Rat CYP2F4
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