Epidemiological Surveillance of Tuberculosis: from Molecular Methods to Genomic Studies-Reference-Cited by-同舟云学术

Epidemiological Surveillance of Tuberculosis: from Molecular Methods to Genomic Studies

Published:2024-01-06 Issue:6 Volume:22 Page:155-161
ISSN:2619-0494
Container-title:Epidemiology and Vaccinal Prevention
language:
Short-container-title:Epidemiology and Vaccinal Prevention

Author:

Ogarkov O. B.¹^ORCID,Savilov E. D.¹^ORCID,Zhdanova S. N.¹^ORCID

Affiliation:

1. Scientific Centre for Family Health and Human Reproduction Problems

Abstract

Relevance. The globalization of the epidemic process requires improved surveillance of infectious diseases, in particular tuberculosis.Methods of molecular and genomic analysis are the most informative approaches that can radically change the management of this disease.Aims. To substantiate the necessary and sufficient volume of molecular studies for the exhaustive detection of most epidemic genotypes of Mycobacterium tuberculosis in Russia and the countries of the former USSR.Conclusions. Genetic lines L2 (Beijing) and L4 (Euro-American) cover more than 95% of all epidemic genotypes of M. tuberculosis in Russia and the countries of the former USSR. The development of rapid tests compatible with global data on genomic polymorphism will make it possible to conduct an epidemiological analysis of tuberculosis outbreaks within the country and to differ from cases of transbordern transmission of new genotypes outside.

Publisher

LLC Numicom

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health,Epidemiology

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