Evaluation of the Effectiveness of Vaccination of Russian Railways employees

Author:

Kostenko N. A.1ORCID,Jidkova E. A.2ORCID,Goriaev A. A.3ORCID,Shangin I. V.3ORCID,Khaltourina D. A.4ORCID,Matveyev Y. N.5ORCID,Ustyuzhanin V. V.6ORCID,Gurevich K. G.7ORCID

Affiliation:

1. JSC "Russian Railways"; Federal Research Budgetary Scientific Institution "Izmerov Research Institute of Occupational Health"

2. JSC "Russian Railways"; The Moscow State University of Medicine and Dentistry;

3. JSC "Russian Railways"

4. Federal Research Institute for Health Organization and Informatics of Ministry of Health of the Russian Federation

5. Moscow Regional Research and Clinical Institute

6. National Research University Higher School of Economics

7. The Moscow State University of Medicine and Dentistry; Research Institute of Health Organization and Medical Management of the Moscow City Health Department

Abstract

Relevance. The effectiveness of vaccination of the working population against COVID-19 in the Russian background has not been studied enough.Aim. To evaluate the effectiveness of vaccination of the working population with Gam-COVID-Vak (Sputnik V) in the Russian Railways as an example.Materials & Methods.The effectiveness of vaccination with Sputnik V among employees of Russian Railways in the period from January 21 to November 31, 2021 was performed with the Cox regression method.Results. The effectiveness of Sputnik V against COVID-19 infection with was 97.8% (95% CI 97.8–97.9%) for two doses, 91.9% (95% CI 91.6–92.2%) for a single dose, and 97.9% (95% CI 97.6–98.1%) for revaccination, all after socio-demographic factors adjusted. The effectiveness of vaccination against COVID-19 with hospitalization was 97.5% for two doses of Sputnik V (95% CI 97.1–97.9%), 86.1% (95% CI 83.7–88.1%) for a single dose, and 98.2% (95% CI 96.3–99.2%) for revaccination. The effectiveness against lethal COVID-19 was 95.2% (95% CI 93.1–96.6%) for two doses of Sputnik V and 94.8% (95% CI 89–97.6%) for one dose. The high efficiency of vaccination could be associated with a fairly young age composition of the employees of the Russian Railways.Conclusions. The study showed the high effectiveness of vaccination with Sputnik V against COVID-19 among the working population.

Publisher

LLC Numicom

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health,Epidemiology

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