A Case of Prepubertal Ovarian Tissue Cryopreservation in Metachronous Bilateral Mature Ovarian Teratoma Requiring Bilateral Oophorectomy

Author:

Malik Tom1,Wheeler Robert2,Hall Nigel J.3,Gray Juliet4

Affiliation:

1. Department of Paediatric Surgery and Urology, Southampton Children's Hospital, Southampton, United Kingdom

2. Department of Paediatric Surgery, Southampton Children's Hospital, Southampton, United Kingdom

3. Faculty of Medicine, University of Southampton, Southampton, United Kingdom

4. Centre for Cancer Immunology, Faculty of Medicine, University of Southampton, Southampton, United Kingdom

Abstract

AbstractMature ovarian teratoma has the potential to occur metachronously in the contralateral ovary. There are significant implications for fertility as bilateral oophorectomy may be indicated. In prepubertal girls, ovarian tissue cryopreservation (OTC) offers the only possibility of a future biological pregnancy but outcome data are limited. We present a case of prepubertal OTC in a 12-year-old girl undergoing a second oophorectomy for metachronous contralateral mature teratoma. We offer a discussion of the challenges that emerged regarding perioperative decision-making, balancing the need for safe oncological resection with the desire to preserve fertility.

Publisher

Georg Thieme Verlag KG

Subject

General Medicine

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