Supracricoid Partial Laryngectomy: Oncological and Functional Outcomes

Author:

Mesolella Massimo1,Iorio Brigida1,Buono Sarah1,Cimmino Mariano1,Motta Gaetano2

Affiliation:

1. Department of Neuroscience, Reproductive Sciences, and Dentistry, Università di Napoli Federico II, Napoli, Italy

2. Department of Anesthesiology, Surgical, and Emergency Sciences, Head and Neck Surgery Unit, Università degli Studi della Campania Luigi Vanvitelli, Napoli, Italy

Abstract

Abstract Introduction In the present study, we have reviewed the outcomes of patients with supracricoid partial laryngectomy (SCPL) in our institution. Our results show that SCPL is a well-tolerated procedure with generally good functional outcomes for patients with advanced laryngeal cancer. Objective We analyzed the oncological and functional results of a cohort of 35 patients who had undergone SCPL, and we highlighted the complications, identified the overall and disease-free survivals, demonstrating that the reconstructive laryngectomy guarantees the oncological safety and reproducibility of the oncological results, preserving the laryngeal functions and promoting an improvement in the patient's quality of life, favoring communication and interpersonal relationships. Methods Between 2010 and 2018, 35 patients underwent SCPL for primary and recurrent laryngeal squamous cell carcinomas, and they were divided into two subgroups: in 16 cases, the cricohyoidoepiglottopexy according to the Mayer-Piquet technique was performed, while the remaining 19 cases were submitted to the cricohyoidopexy according to the Labayle technique. In addition to evaluating the oncological results of patients undergoing reconstructive laryngectomy, the present study also aimed to evaluate the functionality of the residual larynx and the quality of life. Results The overall and disease-free survivals were of 83% and 76.3% respectively. All patients were able to swallow. The nasogastric tube was removed after a mean period of 21.8 days (range: 14 to 28 days). The mean decannulation time was of 23.4 days after surgery (range: 15 to 36 days). Conclusion The curves for the overall and disease-free survivals show that SCPL can guarantee oncological safety comparable to that of total laryngectomies in diseases in the intermediate stage and in carefully-selected advanced stages.

Publisher

Georg Thieme Verlag KG

Subject

Otorhinolaryngology

Reference23 articles.

1. Les laryngectomies subtotales fonctionnelles avec CHP;J J Piquet;Ann Otolaryngol,1986

2. Total laryngectomy with reconstitution;J Labayle;Ann Otolaryngol Chir Cervicofac,1971

3. The development and validation of a dysphagia-specific quality-of-life questionnaire for patients with head and neck cancer: the M. D. Anderson dysphagia inventory;A Y Chen;Arch Otolaryngol Head Neck Surg,2001

4. Validation of the EORTC QLQ-C30 and EORTC QLQ-H&N35 in patients with laryngeal cancer after surgery;S Singer;Head Neck,2009

5. Statistical power as a function of Cronbach alpha of instrument questionnaire items;M Heo;BMC Med Res Methodol,2015

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