Affiliation:
1. Institute of Pharmacy, Pranveer Singh Institute of Technology, Bhauti,
Kanpur, Uttar Pradesh, India
2. Department of Pharmacology, JSS College of Pharmacy, JSS Academy of
Higher Education & Research, Ooty, Nilgiris, Tamil Nadu,
India
Abstract
AbstractResveratrol (RSV), the most effective stilbene phytoalexin synthesized naturally
or induced in plants as part of their defense mechanism, is a key component
of natural phenolic compounds and is being considered as a treatment
option for a variety of diseases. RSV was discovered in the skin of red grapes,
mulberries, peanuts, pines, and Polygonum cuspidatum weed root extracts.
It was first extracted from white hellebore (Veratrum grandiflorum O.
Loes) roots in 1940, then from Polygonum cuspidatum roots in
1963. However, RSV’s use as a drug is limited due to its initial
conformational strength and poor stability. The research focused on a set of RSV
biological activity data. RSV has been the subject of growing concern, despite
its wide range of biological and therapeutic applications. According to the
literature, RSV has antioxidant, anti-cancer, cardioprotective, neuroprotective,
anti- inflammatory, anti-microbial, immunomodulatory, and radioprotective
properties. The current analysis summarized biological applications of RSV,
their mechanisms of action, and recent scientific development in the
area of their delivery. It is possible to infer that RSV has many effects on
infected cells’ cellular functions.
Funder
financially supported by the author.
Subject
Drug Discovery,General Medicine
Cited by
25 articles.
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