Electrochemical Cyclization of Hydrazones and Amidines To Access Trisubstituted 1,2,4-Triazoles

Author:

Tang Dong12ORCID,Jiang Rui1,Mu Yangxiu1,Hou Jing1,Wan Yaya1,Hong Yu1,Yang Zhixiang1

Affiliation:

1. Institute of Agricultural Resources and Environment, Ningxia Academy of Agriculture and Forestry Science

2. Department of Chemical and Material Engineering, Quzhou College of Technology

Abstract

AbstractA KI-mediated electrochemical method has been developed for the synthesis of trisubstituted 1,2,4-triazoles from easily accessible hydrazones and amidines derivatives. The protocol provides various aryl and alkyl 1,2,4-triazoles in moderate to good yields with good functional-group tolerance and without the need for any chemical oxidants in an undivided cell.

Funder

Natural Science Foundation of Ningxia Province

Key Research and Development Program of Ningxia

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry

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