Facile Construction of Troponoid Derivatives Incorporating Imidazolin-2-one Moieties

Author:

Yu Jing1,Chen Xiaobei2,Hu Yanwei1,Wang Liang3,Zhang Shilei1,Liu Ye1,Wu Bing4,Li Haiyan4

Affiliation:

1. Jiangsu Key Laboratory of Neuropsychiatric Diseases & College of Pharmaceutical Sciences, Soochow University

2. State Key Laboratory of Bioengineering Reactor, and Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science & Technology

3. College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University

4. College of Chemistry, Chemical Engineering and Materials Science, Soochow University

Abstract

Troponoid derivatives incorporating imidazolin-2-one moieties were efficiently constructed via a cascade process, under simple thermal conditions, which features a novel nitrogen source, is catalyst- and oxidant-free, and has high atom- and step-economy.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Shandong Province

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry,Catalysis

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