Prevalence of sonographic signs in women with uterine sarcoma: a systematic review and meta-analysis

Author:

Raffone Antonio1ORCID,Raimondo Diego2ORCID,Neola Daniele3,Travaglino Antonio4,Doglioli Marisol12,Ambrosio Marco5,Raimondo Ivano6,De Meis Lucia2,Turco Luigi Carlo4,Cosentino Francesco7,Seracchioli Renato12,Casadio Paolo2,Mollo Antonio8

Affiliation:

1. Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy

2. Division of Gynaecology and Human Reproduction Physiopathology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy

3. Department of Neuroscience, Reproductive Sciences and Dentistry, University of Naples Federico II, Napoli, Italy

4. Department of Woman’s Health Science, University Hospital Agostino Gemelli, Roma, Italy

5. Mother-Child Department, Azienda Unità Sanitaria Locale di Bologna, Bologna, Italy

6. Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy

7. Department of Medicine and Health Science, University of Molise, Campobasso, Italy

8. Department of Medicine, Surgery and Dentistry "Schola Medica Salernitana", University of Salerno, Fisciano, Italy

Abstract

Abstract Objective To assess the prevalence of sonographic signs in women with uterine sarcoma. Materials and Methods A systematic review and meta-analysis were performed. Five electronic databases were searched from inception to June 2022 for all studies allowing calculation of the prevalence of sonographic signs in women with uterine sarcoma. Pooled prevalence with 95% confidence intervals was calculated for each sonographic sign and was a priori defined as “very high” when it was ≥ 80%, “high” when it ranged from 80% to 70%, and less relevant when it was ≤ 70%. Results 6 studies with 317 sarcoma patients were included. The pooled prevalence was: Conclusion Solid component, irregular walls of cystic areas, and singular lesions are signs with very high prevalence, while inhomogeneous echogenicity of solid component, anechoic cystic areas, and absence of calcifications are signs with high prevalence. The remaining signs were less relevant.

Publisher

Georg Thieme Verlag KG

Subject

Radiology, Nuclear Medicine and imaging

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