Affiliation:
1. Department of Chemistry, Nanchang University
Abstract
A facile bisphosphorylation of amino-2-en-1-ones with trialkyl phosphites mediated by iron is developed. The reaction is considered to go through two Michael addition progresses. A variety of amino-2-en-1-ones are bisphosphorylated in high yields with functional group tolerance. In addition, the protocol of introduction of two different phosphates into one molecule is successful through a cascade reaction.
Funder
National Natural Science Foundation of China
Cited by
6 articles.
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