A Novel One-Pot, Two-Step Reaction for the Synthesis of Indenopyrrolo[3,2-c]pyridinone Derivatives with a Recyclable Catalyst

Abstract

An efficient strategy was developed for the synthesis of indenopyrrolopyridinone derivatives from 4-hydroxy-6-methyl-2H-pyran-2-one, an amine, and 2,2-dihydroxy-1H-indene-1,3(2H)-dione by a one-pot, two-step, four-component process. The one-pot reaction gives various substituted indenopyrrolopyridinones in good yields and uses a solid acid as a recyclable catalyst in water. This procedure has the advantages of inexpensive substrates, a reusable solid-supported catalyst, and a convenient one-pot operation.