Angiotensin II Type 1 Receptor Autoantibodies in Primary Aldosteronism-Reference-Cited by-同舟云学术

Angiotensin II Type 1 Receptor Autoantibodies in Primary Aldosteronism

Published:2020-03-13 Issue:06 Volume:52 Page:379-385
ISSN:0018-5043
Container-title:Hormone and Metabolic Research
language:en
Short-container-title:Horm Metab Res

Author:

Meyer Lucie S.¹,Gong Siyuan¹,Reincke Martin¹,Williams Tracy Ann¹²

Affiliation:

1. Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Germany

2. Division of Internal Medicine and Hypertension, Department of Medical Sciences, University of Turin, Turin, Italy

Abstract

AbstractPrimary aldosteronism (PA) is the most common form of endocrine hypertension. Agonistic autoantibodies against the angiotensin II type 1 receptor (AT1R-Abs) have been described in transplantation medicine and women with pre-eclampsia and more recently in patients with PA. Any functional role of AT1R-Abs in either of the two main subtypes of PA (aldosterone-producing adenoma or bilateral adrenal hyperplasia) requires clarification. In this review, we discuss the studies performed to date on AT1R-Abs in PA.

Funder

The European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme

The Deutsche Forschungsgemeinschaft

Publisher

Georg Thieme Verlag KG

Subject

Biochemistry, medical,Clinical Biochemistry,Endocrinology,Biochemistry,General Medicine,Endocrinology, Diabetes and Metabolism

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/a-1120-8647.pdf

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