The Preparation and Application of Diaryliodonium Salts Derived from Gemfibrozil and Gemfibrozil Methyl Ester-Reference-Cited by-同舟云学术

The Preparation and Application of Diaryliodonium Salts Derived from Gemfibrozil and Gemfibrozil Methyl Ester

Published:2021-10-27 Issue: Volume: Page:
ISSN:0039-7881
Container-title:Synthesis
language:en
Short-container-title:Synthesis

Author:

Wu Panpan¹²,Chen Chao¹²³⁴,Zhou Jun¹²,Bao Zhiyuan³

Affiliation:

1. School of Biotechnology and Health Sciences, Wuyi University

2. International Healthcare Innovation Institute (Jiangmen)

3. Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University

4. State Key Laboratory of Elemento-Organic Chemistry, Nankai University

Abstract

AbstractThe diaryliodonium salts derived from gemfibrozil and gemfibrozil methyl ester were synthesized from ArI(OH)OTs or bis(4-methoxyphenyl)iodonium diacetate with good regioselectivity. These iodonium salts were successfully used in the derivatization of gemfibrozil or gemfibrozil methyl ester, including fluorination, alkynylation, arylation, etherification, esterification, and iodination reactions.

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Department of Education of Guangdong Province

Wuyi University

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry,Catalysis

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/a-1679-7753.pdf

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