Mild and Direct C–H Arylation of Quinoxalin-2(1H)-ones with Aryldiazonium Salts under Metal-Free Conditions

Author:

Zhang Ronghua12ORCID,Yin Kun1

Affiliation:

1. School of Chemical Science and Engineering, Tongji University

2. Shanghai Key Lab of Chemical Assessment and Sustainability, Tongji University

Abstract

A mild and direct C–H arylation of quinoxazolin-2(1H)-ones with aryldiazonium salts has been developed. A wide variety of 3-arylquinoxazolin-2(1H)-ones were synthesized in up to 92% yield at room temperature under metal-free conditions. This strategy tolerates a wide range of functional groups and shows environmental friendliness and practicality.

Funder

National Nature Science Foundation of China

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry

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