Radiological Features of Zollinger–Ellison Syndrome: A Report of Two Cases

Author:

Pratap Thara1ORCID,Jalal Muhammed Jasim Abdul2,Jacob Dhanya1,Mahadevan Pushpa3,Nair Seethal S.1,Raja Senthil4

Affiliation:

1. Department of Radiology, VPS Lakeshore Hospital, Kochi, Kerala, India

2. Department of Internal Medicine and Rheumatology, VPS Lakeshore Hospital, Kochi, Kerala, India

3. Department of Pathology, VPS Lakeshore Hospital, Kochi, Kerala, India

4. Department of Nuclear Medicine, VPS Lakeshore Hospital, Kochi, Kerala, India

Abstract

AbstractHypersecretion of gastrin from duodenal or pancreatic gastrinomas results in a rare clinical entity called Zollinger–Ellison syndrome (ZES). It mostly presents with abdominal pain and diarrhea. ZES may be sporadic or occur in association with multiple endocrine neoplasia type 1. Usually, ZES manifests between 20 and 50 years.We report two cases of patients who presented with abdominal pain, vomiting, watery diarrhea, and significant weight loss.

Publisher

Georg Thieme Verlag KG

Subject

Radiology, Nuclear Medicine and imaging

Reference16 articles.

1. A perplexing case of abdominal pain that led to the diagnosis of Zollinger-Ellison syndrome;A Lenhart;Case Rep Gastrointest Med,2017

2. An unusual presentation of zollinger-ellison syndrome;E Sinagra;Case Rep Gastroenterol,2013

3. Serum gastrin in Zollinger-Ellison syndrome: I. Prospective study of fasting serum gastrin in 309 patients from the National Institutes of Health and comparison with 2229 cases from the literature;M J Berna;Medicine (Baltimore),2006

4. Zollinger-Ellison syndrome: revelation of the gastrinoma triangle;R H Yang;Radiol Case Rep,2015

5. Gastrinoma (duodenal and pancreatic);R T Jensen;Neuroendocrinology,2006

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