Literature Review: Role of Neurosurgery in Leptomeningeal Carcinomatosis

Author:

Ogasawara Thaís Mitie1ORCID,Batista Thaís Yumi KobayashiORCID,dos Santos Rafael Rodrigues Pinheiro1ORCID,Rampazzo Ana Carla Mondek1ORCID,Badaoui Caroline Amane Pessoa1ORCID,Caetano Igor Ruan de Araújo1ORCID,Martins Jonathan Vinícius1ORCID,Nogueira Maria Letícia1ORCID,Guarnieri José Ângelo2ORCID,Zicarelli Carlos Alexandre Martins3456ORCID

Affiliation:

1. Department of Neuroscience, Pontifícia Universidade Católica do Paraná, Londrina, Paraná, Brazil

2. Neurosurgery Residency, Hospital Evangélico de Londrina, Londrina, Paraná, Brazil

3. Department of Neurosurgery, Hospital Evangélico de Londrina, Londrina, Paraná, Brazil

4. Medical Internship, Pontifícia Universidade Católica do Paraná, Londrina, Paraná, Brazil

5. Rehabilitation Science Program, Universidade Estadual de Londrina, Londrina, Paraná, Brazil

6. Department of Health and Rehabilitation, Universidade Norte do Paraná, Londrina, Paraná, Brazil

Abstract

Abstract Introduction Leptomeningeal carcinomatosis results from metastatic neoplastic cells that reach the leptomeninges through the cerebrospinal fluid. The presentation of the disease is variable, making prognosis challenging. However, the presence of intracranial hypertension is common, which has prompted new treatments to mitigate this effect. Objective To report the role of neurosurgery in the treatment of leptomeningeal carcinomatosis, as well as its advances. Methodology Literature review with a search of the PubMed database, between 2011 and 2021, using the following descriptors: Neurosurgery, Leptomeningeal Carcinomatosis, Cerebrospinal and Treatment. A total of 42 articles were found, 16 of which were selected. Results The shunt insertion considerably improved the effects of cranial hypertension, increasing the average survival time of patients by 3.5 months after surgery. The Ommaya reservoir is also a viable option due to its convenience and safety. The V-Port, on the other hand, has overcome the challenges of conventional devices, with shorter operating times (42 minutes), smaller skin incisions, and no reports of postoperative infection. Conclusion Devices for the treatment of leptomeningeal carcinomatosis have been steadily improving, simplifying surgical procedures and benefiting patients.

Publisher

Georg Thieme Verlag KG

Subject

Neurology (clinical),Surgery

Reference17 articles.

1. A case of difficult-to-diagnose carcinomatous meningitis caused by prostate cancer metastasis;M Shinohara;Hinyokika Kiyo,2016

2. Effects of postoperative radiotherapy on leptomeningeal carcinomatosis or dural metastasis after resection of brain metastases in breast cancer patients;B Ha;Cancer Res Treat,2017

3. Clinical outcome of cerebrospinal fluid shunts in patients with leptomeningeal carcinomatosis;H S Kim;World J Surg Oncol,2019

4. Diagnosis and treatment patterns for patients with leptomeningeal metastasis from solid tumors across Europe;E Le Rhun;J Neurooncol,2017

5. Leptomeningeal carcinomatosis: easy to miss;A Sekhar;J R Coll Physicians Edinb,2017

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3