Affiliation:
1. School of Health Sciences, University of Greenwich
Abstract
Background: Many chronic conditions in humans, including inflammatory bowel disease and irritable bowel syndrome, have been linked to an imbalance in the gut microbial ecosystem. The maintenance of healthy gut microbiota involving the use of prebiotics may contribute to eubiosis, which could be useful in promoting gastrointestinal health. This systemic review aims to examine the role of prebiotics in gastrointestinal health. Method: The systematic review was conducted based on the PRISMA framework. Searches were carried out in electronic databases including Health Sciences Research Databases, EMBASE and the reference list of articles. The PICO tool was used to develop the search terms and the results of the searches were screened for eligibility based on inclusion and the exclusion criteria. Results: Seven randomised controlled studies were included in the systematic review. Following the review of the results of the studies included, three distinct areas were identified. Conclusions: This systematic review has demonstrated that prebiotics are effective in promoting the relative abundance of Bifidobacterium and gastrointestinal health with minimal discomfort, although the type and amount of prebiotics are important factors.