Affiliation:
1. Department of Anesthesiology
2. Division of Cardiothoracic Surgery, University Hospitals of Cleveland/Case Western Reserve University School of Medicine
Abstract
The ability to perform surgical procedures on the heart was one of the greatest accomplishments of the 20th century. What was once considered an impossible task has become a routine in daily clinical activity. The in troduction of extracorporeal circulation and myocardial protection strategies opened the doors to what was considered by most an insurmountable barrier— unhin dered access to the coronary circulation and intracar diac structures. In the United States, approximately 85% of coronary artery bypass graft procedures are performed with the use of cardiopulmonary bypass (CPB). CPB was and remains the gold standard for this type of cardiac surgical intervention. Over the years, investigators have struggled to find ways of lessening or eliminating the adverse physiologic effects of CPB. These efforts have focused on pharmacologic interven tion, monitoring procedures, blood gas management, and temperature management. Another way of avoid ing these effects is inherently obvious — eliminate the main source of the problem.
Subject
Anesthesiology and Pain Medicine,Cardiology and Cardiovascular Medicine