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Elevated APE1 Dysregulates Homologous Recombination and Cell Cycle Driving Genomic Evolution, Tumorigenesis, and Chemoresistance in Esophageal Adenocarcinoma

  • Published:2023-08 Issue:2 Volume:165 Page:357-373
  • ISSN:0016-5085
  • Container-title:Gastroenterology
  • language:en
  • Short-container-title:Gastroenterology

Author:

Kumar Subodh,Zhao Jiangning,Talluri Srikanth,Buon Leutz,Mu Shidai,Potluri Lakshmi B.,Liao Chengcheng,Shi Jialan,Chakraborty Chandraditya,Gonzalez Gabriel B.,Tai Yu-Tzu,Patel Jaymin,Pal Jagannath,Mashimo Hiroshi,Samur Mehmet K.,Munshi Nikhil C.,Shammas Masood A.ORCID

Funder

National Institutes of Health

U.S. Department of Veterans Affairs

Leukemia and Lymphoma Society

National Natural Science Foundation of China

Natural Science Foundation of Guangxi Province

Publisher

Elsevier BV

Subject

Gastroenterology,Hepatology

Reference73 articles.

1. Genomic instability and colon cancer;Grady;Cancer Metastasis Rev,2004

2. [Genomic instability in multiple myeloma];Kawano;Nihon Rinsho,2007

3. Chromosomal instability and copy number alterations in Barrett's esophagus and esophageal adenocarcinoma;Paulson;Clin Cancer Res,2009

4. Genomic instability in multiple myeloma: evidence for jumping segmental duplications of chromosome arm 1q;Sawyer;Genes Chromosomes Cancer,2005

5. Genomic instability—the engine of tumorigenesis?;Sieber;Nat Rev Cancer,2003
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