NF-κB inhibition sensitizes hepatocytes to TNF-induced apoptosis through a sustained activation of JNK and c-Jun
Author:
Funder
National Institutes of Health
Publisher
Wiley
Subject
Hepatology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1053/jhep.2002.32534/fullpdf
Reference34 articles.
1. Tumor necrosis factor-induced apoptosis during the poisoning of mice with hepatotoxins;Leist;Gastroenterology,1997
2. NF-κB inactivation converts a hepatocyte cell line TNF-α response from proliferation to apoptosis;Xu;Am J Physiol,1998
3. The mitochondrial permeability transition is required for tumor necrosis factor alpha-mediated apoptosis and cytochrome c release;Bradham;Mol Cell Biol,1998
4. Inhibition of c-Myc expression sensitizes hepatocytes to tumor necrosis factor-induced apoptosis and necrosis;Liu;J Biol Chem,2000
5. Hepatocytes sensitized to TNF-α cytotoxicity undergo apoptosis through caspase-dependent and caspase-independent pathways;Jones;J Biol Chem,2000
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