Platelet reactivity to thrombin differs between patients with COVID-19 and those with ARDS unrelated to COVID-19

Author:

Zaid Younes123ORCID,Guessous Fadila45,Puhm Florian67,Elhamdani Wail1,Chentoufi Lamyae1,Morris Andrew Conway8ORCID,Cheikh Amine1,Jalali Farid9,Boilard Eric67,Flamand Louis67ORCID

Affiliation:

1. Research Center of Abulcasis University of Health Sciences, Cheikh Zaïd Hospital, Rabat, Morocco;

2. Biology Department, Faculty of Sciences, Mohammed V University in Rabat, Rabat, Morocco;

3. Immunology and Biodiversity Laboratory, Department of Biology, Faculty of Sciences Ain Chock, Hassan II University, Casablanca, Morocco;

4. Department of Microbiology, Immunology and Cancer Biology, School of Medicine, University of Virginia, Charlottesville, VA;

5. Research Center, Faculty of Medicine, Mohammed VI University of Health Sciences, Casablanca, Morocco;

6. Centre de Recherche du Centre Hospitalier Universitaire de Québec–Université Laval, Québec, QC, Canada;

7. Département de Microbiologie-Infectiologie et d’Immunologie, Université Laval, Québec, QC, Canada;

8. Division of Immunology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom; and

9. Department of Gastroenterology, Saddleback Medical Group, Laguna Hills, CA

Publisher

American Society of Hematology

Subject

Hematology

Reference25 articles.

1. Neutrophils scan for activated platelets to initiate inflammation;Sreeramkumar;Science,2014

2. Neutrophil extracellular traps in pulmonary diseases: too much of a good thing?;Porto;Front Immunol,2016

3. Amicus or adversary revisited: platelets in acute lung injury and acute respiratory distress syndrome;Middleton;Am J Respir Cell Mol Biol,2018

4. Disruption of platelet-derived chemokine heteromers prevents neutrophil extravasation in acute lung injury;Grommes;Am J Respir Crit Care Med,2012

5. Platelet depletion and aspirin treatment protect mice in a two-event model of transfusion-related acute lung injury;Looney;J Clin Invest,2009

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