TCF1 expression marks self-renewing human CD8+ T cells-Reference-Cited by-同舟云学术

TCF1 expression marks self-renewing human CD8+ T cells

Published:2018-07-18 Issue:14 Volume:2 Page:1685-1690
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Kratchmarov Radomir¹²,Magun Arthur M.³,Reiner Steven L.¹²^ORCID

Affiliation:

1. Department of Microbiology and Immunology and

2. Department of Pediatrics, Roy and Diana Vagelos College of Physicians and Surgeons, Columbia University, New York, NY;

3. Division of Digestive and Liver Diseases, Department of Medicine, Columbia University Medical Center, New York, NY

Abstract

Key Points Human blood CD8+ T cells express distinct levels of TCF1, defining quiescent vs effector populations. TCF1-hi cells proliferate and uniquely self-renew following T-cell receptor stimulation to produce both TCF1-hi and TCF1-low cells.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/2/14/1685/881060/advances016279.pdf

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