1. US Food and Drug Administration, White Oak, MD;
2. Pediatric Hematology, Medical College of Wisconsin/Children's Wisconsin, Milwaukee, WI;
3. Krannert Institute of Cardiology, Department of Medicine, Indiana University, Indianapolis, IN;
4. Division of Hematology/Oncology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN;
5. Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL;
6. UCSF Benioff Children’s Hospital, Oakland, CA;
7. Division of Hematology/Oncology, Boston Children’s Hospital, Boston, MA;
8. Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA;
9. Department of Pediatrics, Harvard Medical School, Boston, MA;
10. Children’s Hospitals and Clinics of MN, Minneapolis, MN;
11. Sickle Cell Foundation of Minnesota, Minneapolis, MN;
12. National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD;
13. Pittsburgh Heart, Lung, and Blood Vascular Medicine Institute, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA;
14. Department of Pediatrics, Columbia University Medical Center, New York, NY;
15. Division of Hematology, Department of Medicine, University of Colorado, Aurora, CO;
16. Division of Hematology-Oncology and Pittsburgh Heart, Lung, Blood and Vascular Medicine Institute, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA;
17. The Pulmonary Center, Boston University School of Medicine, Boston, MA;
18. Department of Microbiology, Immunology & Molecular Genetics,
19. Department of Pediatrics, and
20. Department of Molecular & Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA;
21. Aflac Cancer and Blood Disorders Center, Emory University, Children's Healthcare of Atlanta, Atlanta, GA;
22. Hematology/Oncology, Department of Medicine, University of North Carolina, Chapel Hill, NC;
23. Department of Haematology and Blood Transfusion, School of Medicine, Muhimbili University of Health and Allied Sciences, Dar-es-Salaam, Tanzania;
24. Cancer and Blood Disease Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH;
25. Department of Pediatrics, University of Cincinnati, Cincinnati, OH;
26. Division of Hematology, Montefiore Health System, Albert Einstein College of Medicine, New York, NY;
27. Division of Pediatric Emergency Medicine, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA;
28. Children’s Healthcare of Atlanta, Atlanta, GA;
29. The Hospital for Sick Children, Toronto, ON, Canada;
30. University of Toronto, Toronto, ON, Canada;
31. Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, MD; and
32. Division of Pediatric Hematology Oncology and Stem Cell Transplant, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO