Differential antibacterial control by neutrophil subsets-Reference-Cited by-同舟云学术

Differential antibacterial control by neutrophil subsets

Published:2018-06-12 Issue:11 Volume:2 Page:1344-1355
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Leliefeld Pieter H. C.¹²^ORCID,Pillay Janesh²³^ORCID,Vrisekoop Nienke²³^ORCID,Heeres Marjolein¹²,Tak Tamar²³^ORCID,Kox Matthijs⁴^ORCID,Rooijakkers Suzan H. M.⁵^ORCID,Kuijpers Taco W.⁶,Pickkers Peter⁴^ORCID,Leenen Luke P. H.¹²^ORCID,Koenderman Leo²³^ORCID

Affiliation:

1. Department of Surgery,

2. Laboratory of Translational Immunology, and

3. Department of Respiratory Medicine, University Medical Center Utrecht, Utrecht, The Netherlands;

4. Department of Intensive Care, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands;

5. Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands; and

6. Emma Children’s Hospital, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

Abstract

Key PointsNeutrophil subsets circulating during acute inflammation are characterized by differential bacterial containment capacity. Adequate antimicrobial containment is associated with profound phagosomal acidification yet independent of reactive oxygen species.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/2/11/1344/882231/advances015578.pdf

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