Jun-regulated genes promote interaction of diffuse large B-cell lymphoma with the microenvironment-Reference-Cited by-同舟云学术

Jun-regulated genes promote interaction of diffuse large B-cell lymphoma with the microenvironment

Published:2015-02-05 Issue:6 Volume:125 Page:981-991
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Blonska Marzenna¹²,Zhu Yifan¹,Chuang Hubert H.³,You M. James²⁴,Kunkalla Kranthi⁵,Vega Francisco⁵,Lin Xin¹²⁶

Affiliation:

1. Department of Molecular and Cellular Oncology,

2. Center for Inflammation and Cancer,

3. Department of Nuclear Medicine, and

4. Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX;

5. Department of Pathology, Sylvester Cancer Center, University of Miami, Miami, FL; and

6. Cancer Biology Program, The University of Texas Graduate School of Biomedical Sciences, Houston, TX

Abstract

Key Points Elevated Jun signaling promotes lymphoma growth and dissemination to extranodal sites. Jun-regulated genes mediate the interaction of malignant cells with stromal cells and adhesion to extracellular matrix proteins.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/125/6/981/1387818/981.pdf

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4. A loss-of-function RNA interference screen for molecular targets in cancer.;Ngo;Nature,2006

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