Recombinant factor VIII products and inhibitor development in previously untreated boys with severe hemophilia A-Reference-Cited by-同舟云学术

Recombinant factor VIII products and inhibitor development in previously untreated boys with severe hemophilia A

Published:2014-11-27 Issue:23 Volume:124 Page:3398-3408
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Calvez Thierry¹²,Chambost Hervé³⁴,Claeyssens-Donadel Ségolène⁵,d’Oiron Roseline⁶,Goulet Véronique⁷,Guillet Benoît⁸,Héritier Virginie⁷,Milien Vanessa³,Rothschild Chantal⁹,Roussel-Robert Valérie¹⁰,Vinciguerra Christine¹¹,Goudemand Jenny¹²

Affiliation:

1. Sorbonne Universités, Université Pierre et Marie Curie Paris 06, Unité Mixte de Recherche en Santé 1136, Institut Pierre Louis d’Épidemiologie et de Santé Publique, Paris, France;

2. INSERM, Unité Mixte de Recherche en Santé 1136, Institut Pierre Louis d’Épidemiologie et de Santé Publique, Paris, France;

3. Service d’Hématologie Oncologie Pédiatrique, La Timone, Assistance Publique-Hôpitaux de Marseille, Marseille, France;

4. INSERM, Unité Mixte de Recherche 1062, Faculté de Médecine, Aix-Marseille Université, Marseille, France;

5. Centre Régional d’Hémophilie, Centre Hospitalier Universitaire, Toulouse, France;

6. Centre Régional d’Hémophilie, Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Le Kremlin Bicêtre, France;

7. French Institute for Public Health Surveillance, Saint-Maurice, France;

8. Centre Régional de Traitement des Maladies Hémorragiques de Rennes-Bretagne, Centre Hospitalier Universitaire de Rennes et Rennes 1 Université, Faculté de Médecine, Rennes, France;

9. Centre Régional d’Hémophilie, Assistance Publique-Hôpitaux de Paris, Centre Hospitalier Universitaire de Necker, Paris, France;

10. Centre Régional d’Hémophilie, Assistance Publique-Hôpitaux de Paris, Centre Hospitalier Universitaire de Cochin, Paris, France;

11. Service d’Hématologie Biologique, Hospices Civils de Lyon, Equipe d'Accueil Mixte 4174, Université de Lyon, Lyon, France;

12. Service d’Hématologie et de Transfusion, Centre Hospitalier Universitaire de Lille, Université Lille 2, Equipe d'Accueil 2693, Faculté de Médecine, Lille, France

Abstract

Key Points A currently marketed rFVIII product is associated with a higher risk of inhibitor development in boys with severe hemophilia A. This result, validated by extensive sensitivity analyses, confirms a recently published study and cannot be explained by identified biases.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/124/23/3398/1382196/3398.pdf

Reference46 articles.

1. Hemophilia A.;Hoyer;N Engl J Med,1994

2. Modern haemophilia care.;Berntorp;Lancet,2012

3. The incidence of factor VIII and factor IX inhibitors in the hemophilia population of the UK and their effect on subsequent mortality, 1977-99.;Darby;J Thromb Haemost,2004

4. The diagnosis and management of factor VIII and IX inhibitors: a guideline from the UK Haemophilia Centre Doctors’ Organization (UKHCDO).;Hay;Br J Haematol,2000

5. Current status and future prospects for the prophylactic management of hemophilia patients with inhibitor antibodies.;Teitel;Blood Rev,2013

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