Intravenous immune globulin and thromboembolic adverse events in patients with hematologic malignancy-Reference-Cited by-同舟云学术

Intravenous immune globulin and thromboembolic adverse events in patients with hematologic malignancy

Published:2016-01-14 Issue:2 Volume:127 Page:200-207
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Ammann Eric M.¹^ORCID,Jones Michael P.²,Link Brian K.³,Carnahan Ryan M.¹,Winiecki Scott K.⁴^ORCID,Torner James C.¹,McDowell Bradley D.⁵,Fireman Bruce H.⁶,Chrischilles Elizabeth A.¹⁵

Affiliation:

1. Department of Epidemiology and

2. Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, IA;

3. Division of Hematology, Oncology and Blood & Marrow Transplantation, Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA;

4. Office of Biostatistics and Epidemiology, Center for Biologics Evaluation & Research, US Food and Drug Administration, Silver Spring, MD;

5. Population Research Core, Holden Comprehensive Cancer Center, University of Iowa Hospitals and Clinics, Iowa City, IA; and

6. Division of Research, Kaiser Permanente Northern California, Oakland, CA

Abstract

Key Points Acute myocardial infarction and ischemic stroke risk was 3 times higher during days 0 to 1 following IVIg treatment in patients with secondary hypogammaglobulinemia. In patients treated with IVIg for 1 year, the estimated increase in the absolute risk of a severe thromboembolic event was ∼1%.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/127/2/200/1351924/200.pdf

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